Mark A Giembycz Selected Research

taprostene

3/2011	Evidence for a second receptor for prostacyclin on human airway epithelial cells that mediates inhibition of CXCL9 and CXCL10 release.
11/2009	Selective prostacyclin receptor agonism augments glucocorticoid-induced gene expression in human bronchial epithelial cells.

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Mark A Giembycz Research Topics

Disease

24	Asthma (Bronchial Asthma) 10/2021 - 02/2003
23	Chronic Obstructive Pulmonary Disease (COPD) 01/2021 - 02/2003
6	Inflammation (Inflammations) 01/2022 - 05/2013
5	Lung Diseases (Lung Disease) 01/2021 - 01/2008
4	Necrosis 01/2014 - 12/2003
3	Pneumonia (Pneumonitis) 01/2018 - 04/2010
2	Glucocorticoid Receptor Deficiency 01/2015 - 09/2011
2	Chronic Bronchitis 06/2014 - 07/2010
2	Weight Loss (Weight Reduction) 07/2010 - 04/2010
2	Diarrhea 04/2010 - 01/2005
2	Nausea 04/2010 - 01/2005
2	Eosinophilia 01/2007 - 08/2005
1	Sarcoma (Soft Tissue Sarcoma) 10/2021
1	Fibrosarcoma 10/2021
1	Premature Obstetric Labor (Premature Labor) 07/2012
1	Tics (Tic) 03/2011
1	Headache (Headaches) 07/2010
1	Infections 11/2009
1	Allergic Rhinitis 01/2007
1	Atopic Dermatitis (Atopic Eczema) 01/2007
1	Dyspepsia (Indigestion) 01/2005
1	Arteritis 01/2005
1	Abdominal Pain (Pain, Abdominal) 01/2005
1	Vomiting 01/2005

Drug/Important Bio-Agent (IBA)

13	GlucocorticoidsIBA 01/2021 - 01/2008
12	Phosphodiesterase 4 InhibitorsIBA 01/2019 - 06/2005
11	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2021 - 01/2008
8	RoflumilastIBA 01/2019 - 01/2005
6	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 01/2019 - 02/2003
5	Formoterol Fumarate (Oxis)FDA Link 01/2022 - 04/2013
5	Pharmaceutical PreparationsIBA 01/2021 - 08/2005
4	Type 4 Cyclic Nucleotide PhosphodiesterasesIBA 01/2015 - 01/2005
3	Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA 10/2021 - 01/2005
3	Proteins (Proteins, Gene)FDA Link 01/2019 - 12/2003
3	CytokinesIBA 01/2018 - 01/2009
3	Glucocorticoid Receptors (Glucocorticoid Receptor)IBA 12/2016 - 09/2013
2	Dexamethasone (Maxidex)FDA LinkGeneric 01/2021 - 09/2013
2	Antiviral Agents (Antivirals)IBA 01/2019 - 11/2009
2	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2018 - 01/2014
2	ChemokinesIBA 01/2018 - 01/2009
2	LipopolysaccharidesIBA 01/2018 - 01/2005
2	SmokeIBA 09/2011 - 02/2010
2	taprosteneIBA 03/2011 - 11/2009
2	Bronchodilator Agents (Bronchodilators)IBA 07/2010 - 01/2008
2	Interleukin-8 (Interleukin 8)IBA 09/2008 - 04/2003
2	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 09/2008 - 12/2003
2	ElementsIBA 01/2007 - 08/2005
2	CilomilastIBA 08/2006 - 01/2005
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2005 - 12/2003
1	ArrestinIBA 10/2021
1	beta-Arrestin 1IBA 10/2021
1	Dual Specificity Phosphatase 1IBA 10/2021
1	ONO-AE1-329IBA 01/2021
1	Budesonide (Pulmicort)FDA LinkGeneric 01/2021
1	GTPase-Activating Proteins (GTPase-Activating Protein)IBA 01/2018
1	GTP-Binding Proteins (G-Protein)IBA 01/2018
1	Therapeutic UsesIBA 01/2018
1	Peptide Hydrolases (Proteases)FDA Link 01/2018
1	6- ((3- ((4- (5- ((2- hydroxy- 2- (8- hydroxy- 2- oxo- 1,2- dihydroquinolin- 5- yl)ethyl)amino)pent- 1- yn- 1- yl)phenyl)carbamoyl)phenyl)sulfonyl)- 4- ((3- methoxyphenyl)amino)- 8- methylquinoline- 3- carboxamideIBA 02/2017
1	Hematoxylin (Haematoxylon)IBA 01/2017
1	Eosine Yellowish-(YS) (Eosin)IBA 01/2017
1	Adrenergic Receptors (Adrenergic Receptor)IBA 12/2016
1	Cyclic NucleotidesIBA 06/2014
1	Cyclic AMP (AMP, Cyclic)IBA 06/2014
1	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 01/2014
1	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 01/2014
1	Purinergic P1 Receptor AgonistsIBA 09/2013
1	Adenosine (Adenocard)FDA LinkGeneric 09/2013
1	BAY 60-6583IBA 09/2013
1	Chemokine CXCL9IBA 03/2011
1	Iloprost (Ventavis)FDA Link 03/2011
1	LuciferasesIBA 03/2011
1	Phosphodiesterase InhibitorsIBA 01/2011
1	Salmeterol Xinafoate (Serevent)FDA Link 07/2010
1	Tiotropium Bromide (Spiriva)FDA Link 07/2010
1	Epoprostenol ReceptorsIBA 11/2009
1	Mometasone Furoate (Nasonex)FDA LinkGeneric 08/2009
1	Fluticasone (Cutivate)FDA LinkGeneric 08/2009
1	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 09/2008
1	Interleukin-6 (Interleukin 6)IBA 09/2008
1	diethylstilbestrol monophosphate (PDES)IBA 01/2008
1	Ketotifen (Ketotifene)FDA Link 08/2005
1	SteroidsIBA 01/2005
1	Vasodilator Agents (Vasodilators)IBA 01/2005
1	IsoenzymesIBA 01/2005
1	Phosphotransferases (Kinase)IBA 12/2003
1	MitogensIBA 12/2003
1	Shiga Toxins (Vero Toxin)IBA 12/2003
1	Leukotriene B4IBA 04/2003
1	InterleukinsIBA 04/2003
1	Chemotactic FactorsIBA 04/2003

Therapy/Procedure

16	Therapeutics 01/2021 - 01/2005
1	Ligation 01/2014
1	Induced Labor 07/2012
1	Nebulizers and Vaporizers (Inhaler) 07/2010
1	Drug Therapy (Chemotherapy) 04/2010
1	Dry Powder Inhalers 08/2009